In this episode of the World Nicotine Congress podcast, host Elise Rasmussen speaks with serial entrepreneur and inventor Ryan Selby about investing and innovating in the nicotine sector. With over 17 years of experience and multiple successful exits, including the sale of Poda Holdings’ assets to Altria, Ryan shares insights into developing new nicotine technologies and building companies in one of the world’s most complex and highly regulated industries.

The conversation explores the opportunities for innovation as the industry shifts away from combustible cigarettes toward potentially reduced-risk alternatives. Ryan discusses his approach to product design, the importance of focusing on consumer experience, and why he often partners with larger companies to scale new technologies globally.

They also discuss the realities of entrepreneurship in the sector, including navigating regulation, managing risk, and knowing when the right moment has arrived to exit a business. Ryan also previews the themes he will explore at the World Nicotine Congress in Brussels, where he will moderate a panel on startup investing and emerging technology.